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Article

Functional Dysconnection of the Inferior Frontal Gyrus in Young People With Bipolar Disorder or at Genetic High Risk.

Biological psychiatry - 15 Apr 2017

Roberts Gloria, Lord Anton, Frankland Andrew, Wright Adam, Lau Phoebe, Levy Florence, Lenroot Rhoshel K, Mitchell Philip B, Breakspear Michael

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is characterized by a dysregulation of affect and impaired integration of emotion with cognition. These traits are also expressed in probands at high genetic risk of BD. The inferior frontal gyrus (IFG) is a key cortical hub in the circuits of emotion and cognitive control, and it has been frequently associated with BD. Here, we studied resting-state functional connectivity of...

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PMID: 28031150
DOI: 10.1016/j.biopsych.2016.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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