Article
Connectomic markers of disease expression, genetic risk and resilience in bipolar disorder.
Translational psychiatry - 5 Jan 2016
Dima D, Roberts R E, Frangou S
Abstract excerpt
Bipolar disorder (BD) is characterized by emotional dysregulation and cognitive deficits associated with abnormal connectivity between subcortical-primarily emotional processing regions-and prefrontal regulatory areas. Given the significant contribution of genetic factors to BD, studies in unaffected first-degree relatives can identify neural mechanisms of genetic risk but also resilience, thus paving the way for...
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