Article
RCF1-dependent respiratory supercomplexes are integral for lifespan-maintenance in a fungal ageing model.
Scientific reports - 29 Jul 2015
Fischer Fabian, Filippis Christodoulos, Osiewacz Heinz D
Abstract excerpt
Mitochondrial respiratory supercomplexes (mtRSCs) are stoichiometric assemblies of electron transport chain (ETC) complexes in the inner mitochondrial membrane. They are hypothesized to regulate electron flow, the generation of reactive oxygen species (ROS) and to stabilize ETC complexes. Using the fungal ageing model Podospora anserina, we investigated the impact of homologues of the Saccharomyces cerevisiae...
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