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Article

Proteomic analysis of mitochondria from senescent Podospora anserina casts new light on ROS dependent aging mechanisms.

Experimental gerontology - 1 Aug 2014

Plohnke Nicole, Hamann Andrea, Poetsch Ansgar, Osiewacz Heinz D, Rögner Matthias, Rexroth Sascha

Abstract excerpt

The mitochondrial free radical theory of aging (MFRTA) states that reactive oxygen species (ROS) generated at the respiratory electron transport chain are active in causing age-related damage of biomolecules like lipids, nucleic acids and proteins. Accumulation of this kind of damage results in functional impairments, aging and death of biological systems. Here we report data of an analysis to monitor the...

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PMID: 24556281
DOI: 10.1016/j.exger.2014.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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