Mitochondrial quality control in aging and lifespan control of the fungal aging model <i>Podospora anserina</i>

Abstract excerpt

Aging of biological systems is a fundamental process controlled by a complex network of molecular pathways. In the filamentous fungus Podospora anserina, a model in which organismal aging can conveniently be analysed, mitochondria play a central role. A wide range of relevant pathways were identified that contribute to the maintenance of a population of functional mitochondria. These pathways act in a...