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Article

Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis.

BMC medical genetics - 26 Jul 2015

Numata Shusuke, Kinoshita Makoto, Tajima Atsushi, Nishi Akira, Imoto Issei, Ohmori Tetsuro

Abstract excerpt

BACKGROUND: The results of meta-analyses conducted by previous association studies between total homocysteine and schizophrenia suggest that an elevated total homocysteine level is a risk factor for schizophrenia. However, observational studies have potential limitations, such as confounding and reverse causation. In the present study, we evaluated a causal relationship between plasma total homocysteine and...

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Identifiers

PMID: 26208850
DOI: 10.1186/s12881-015-0197-7
PMCID: PMC4557634

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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