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Article

Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis.

Molecular psychiatry - 1 Feb 2006

Muntjewerff J W, Kahn R S, Blom H J, den Heijer M

Abstract excerpt

Elevated plasma homocysteine concentration has been suggested as a risk factor for schizophrenia, but the results of epidemiological studies have been inconsistent. The most extensively studied genetic variant in the homocysteine metabolism is the 677C>T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene, resulting in reduced enzyme activity and, subsequently, in elevated homocysteine. A...

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Source

Identifiers

PMID: 16172608
DOI: 10.1038/sj.mp.4001746

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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