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Article

Evaluating the causal relationship of Levo-carnitine and risk of schizophrenia: a bidirectional two-sample mendelian randomization study.

BMC psychiatry - 23 Oct 2024

Qiu Haoyuan, Zhong Zicheng, Wu Tianxing, Hu Haoran, Zhou Meijuan, Feng Zhijun

Abstract excerpt

BACKGROUND: Schizophrenia is a debilitating mental disorder affecting about 1% of the global population, characterized by significant cognitive impairments and a strong hereditary component. Carnitine, particularly Levo-carnitine and its derivatives, plays a crucial role in cellular metabolism and mitochondrial function, with evidence suggesting a link between levo-carnitine deficiency and schizophrenia...

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Identifiers

PMID: 39438849
DOI: 10.1186/s12888-024-06177-1
PMCID: PMC11515733

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