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Article

Meta-analyses of blood homocysteine levels for gender and genetic association studies of the MTHFR C677T polymorphism in schizophrenia.

Schizophrenia bulletin - 1 Sept 2014

Nishi Akira, Numata Shusuke, Tajima Atsushi, Kinoshita Makoto, Kikuchi Kumiko, Shimodera Shinji, Tomotake Masahito, Ohi Kazutaka, Hashimoto Ryota, Imoto Issei, Takeda Masatoshi, Ohmori Tetsuro

Abstract excerpt

Previous studies suggest that elevated blood homocysteine levels and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism are risk factors for schizophrenia. However, the effects of gender and MTHFR C677T genotypes on blood homocysteine levels in schizophrenia have not been consistent. We first investigated whether plasma total homocysteine levels were higher in patients with schizophrenia than in...

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Identifiers

PMID: 24535549
DOI: 10.1093/schbul/sbt154
PMCID: PMC4133669

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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