Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma.

Scientific reports - 24 Jul 2015

Mitchell Jonathan S, Johnson David C, Litchfield Kevin, Broderick Peter, Weinhold Niels, Davies Faith E, Gregory Walter A, Jackson Graham H, Kaiser Martin, Morgan Gareth J, Houlston Richard S

Abstract excerpt

A sizeable fraction of multiple myeloma (MM) is expected to be explained by heritable factors. Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleotide polymorphisms (SNPs) influencing MM risk. While these SNPs only explain a small proportion of the genetic risk it is unclear how much is left to be detected by other, yet to be identified, common SNPs. Therefore, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genome-Wide Association Study

Share to Models, Genetic

Share to Multiple Myeloma

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 26208354
DOI: 10.1038/srep12473
PMCID: PMC4513545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma.PMID 26208354Read ↗

A polygenic risk score for multiple myeloma risk prediction.Semantic proximity Read ↗

Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance.Semantic proximity Read ↗

MyelomA Genetics International Consortium.Semantic proximity Read ↗

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.Semantic proximity Read ↗

Identification of novel genetic loci for risk of multiple myeloma by functional annotationSemantic proximity Read ↗

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.Semantic proximity Read ↗

Genetic predisposition for multiple myeloma.Semantic proximity Read ↗

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.Semantic proximity Read ↗

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.Semantic proximity Read ↗

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.Semantic proximity Read ↗

Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Patients with Myeloma?Semantic proximity Read ↗

FaMMily Affairs: Dissecting inherited contributions to multiple myeloma risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.