Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 regulates cytoskeleton remodeling to suppress tumor progression.

Cellular and molecular life sciences : CMLS - 1 Nov 2015

Araki Keigo, Ebata Takahiro, Guo Alvin Kunyao, Tobiume Kei, Wolf Steven John, Kawauchi Keiko

Abstract excerpt

Cancer cells possess unique characteristics such as invasiveness, the ability to undergo epithelial-mesenchymal transition, and an inherent stemness. Cell morphology is altered during these processes and this is highly dependent on actin cytoskeleton remodeling. Regulation of the actin cytoskeleton is, therefore, important for determination of cell fate. Mutations within the TP53 (tumor suppressor p53) gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Cadherins
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cytoskeleton

Share to Integrins

Share to rho GTP-Binding Proteins

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 26206378
DOI: 10.1007/s00018-015-1989-9
PMCID: PMC11114009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 regulates cytoskeleton remodeling to suppress tumor progression.PMID 26206378Read ↗

Gain-of-Function Mutations in p53 in Cancer Invasiveness and Metastasis.Semantic proximity Read ↗

Normal and malignant growth control by p53.Semantic proximity Read ↗

Mutant p53 drives invasion by promoting integrin recycling.Semantic proximity Read ↗

p53 brings a new twist to the Smad signaling network.Semantic proximity Read ↗

p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β.Semantic proximity Read ↗

Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions.Semantic proximity Read ↗

p53's Extended Reach: The Mutant p53 Secretome.Semantic proximity Read ↗

Mutant p53 on the Path to Metastasis.Semantic proximity Read ↗

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signalingSemantic proximity Read ↗

p53 Signaling on Microenvironment and Its Contribution to Tissue ChemoresistanceSemantic proximity Read ↗

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.Semantic proximity Read ↗

Mutant p53 promotes cell spreading and migration via ARHGAP44.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.