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Article

p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β.

Journal of cellular physiology - 1 Apr 2013

Termén Stefan, Tan E-Jean, Heldin Carl-Henrik, Moustakas Aristidis

Abstract excerpt

Epithelial plasticity characterizes embryonic development and diseases such as cancer. Epithelial-mesenchymal transition (EMT) is a reversible and guided process of plasticity whereby embryonic or adult epithelia acquire mesenchymal properties. Multiple signaling pathways control EMT, and the transforming growth factor β (TGFβ) pathway plays a central role as its inducer. Here, we analyzed the role of the tumor...

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Source

Identifiers

PMID: 23018556
DOI: 10.1002/jcp.24229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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