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Article

p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance

9 Feb 2022

Abstract excerpt

Chemoresistance persists as a significant, unresolved clinical challenge in many cancer types. The tumor microenvironment, in which cancer cells reside and interact with non-cancer cells and tissue structures, has a known role in promoting every aspect of tumor progression, including chemoresistance. However, the molecular determinants of microenvironment-driven chemoresistance are mainly unknown. In this review,...

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PMID: 35207121
DOI: 10.3390/membranes12020202

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