Article
Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia.
Scientific reports - 22 Aug 2018
Bunditvorapoom Duangkamon, Kochakarn Theerarat, Kotanan Namfon, Modchang Charin, Kümpornsin Krittikorn, Loesbanluechai Duangkamon, Krasae Thanyaluk, Cui Liwang, Chotivanich Kesinee, White Nicholas J, Wilairat Prapon, Miotto Olivo, Chookajorn Thanat
Abstract excerpt
Artemisinin is the most rapidly effective drug for Plasmodium falciparum malaria treatment currently in clinical use. Emerging artemisinin-resistant parasites pose a great global health risk. At present, the level of artemisinin resistance is still relatively low with evidence pointing towards a trade-off between artemisinin resistance and fitness loss. Here we show that artemisinin-resistant P. falciparum...
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