Article
Genetic variation in insulin-induced kinase signaling.
Molecular systems biology - 22 Jul 2015
Wang Isabel Xiaorong, Ramrattan Girish, Cheung Vivian G
Abstract excerpt
Individual differences in sensitivity to insulin contribute to disease susceptibility including diabetes and metabolic syndrome. Cellular responses to insulin are well studied. However, which steps in these response pathways differ across individuals remains largely unknown. Such knowledge is needed to guide more precise therapeutic interventions. Here, we studied insulin response and found extensive individual...
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