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Article

Gene and MicroRNA Expression Responses to Exercise; Relationship with Insulin Sensitivity

18 May 2015

Abstract excerpt

BACKGROUND: Healthy individuals on the lower end of the insulin sensitivity spectrum also have a reduced gene expression response to exercise for specific genes. The goal of this study was to determine the relationship between insulin sensitivity and exercise-induced gene expression in an unbiased, global manner. METHODS AND FINDINGS: Euglycemic clamps were used to measure insulin sensitivity and muscle biopsies...

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PMID: 25984722
DOI: 10.1371/journal.pone.0127089

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