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Article

Tumor necrosis factor-alpha gene and cerebral aneurysms.

Neurosurgery - 1 Apr 2007

Fontanella Marco, Rainero Innocenzo, Gallone Salvatore, Rubino Elisa, Fenoglio Pierpaola, Valfrè Walter, Garbossa Diego, Carlino Christian, Ducati Alessandro, Pinessi Lorenzo

Abstract excerpt

OBJECTIVE: The pathogenesis of intracranial aneurysms is still uncertain. In addition to atherosclerosis, immunological factors may play a role in the disease. Recent studies have suggested that tumor necrosis factor-alpha (TNF-alpha), one of the main proinflammatory cytokines, may play a key role in the formation and rupture of cerebral aneurysms. The purpose of this study is to evaluate the association of a...

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PMID: 17415203
DOI: 10.1227/01.NEU.0000255417.93678.49

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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