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Article

Alterations of the CD58 gene in classical Hodgkin lymphoma.

Genes, chromosomes & cancer - 1 Oct 2015

Schneider Markus, Schneider Stefanie, Zühlke-Jenisch Reina, Klapper Wolfram, Sundström Christer, Hartmann Sylvia, Hansmann Martin-Leo, Siebert Reiner, Küppers Ralf, Giefing Maciej

Abstract excerpt

Immune evasion plays a central role in the pathophysiology of classical Hodgkin lymphoma (cHL). As mutations of the CD58 gene contribute to immune evasion of diffuse large B cell lymphoma tumor cells, we studied whether alterations of the CD58 gene also occur in Hodgkin and Reed/Sternberg (HRS) cells of cHL. Single nucleotide polymorphism chip analysis revealed homozygous deletions within the CD58 gene in two cHL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26194173
DOI: 10.1002/gcc.22276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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