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Article

HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin's lymphoma.

Tissue antigens - 1 Mar 2008

Diepstra A, Poppema S, Boot M, Visser L, Nolte I M, Niens M, Te Meerman G J, van den Berg A

Abstract excerpt

Classical Hodgkin's lymphoma (cHL) is characterized by the presence of an abundant reactive infiltrate, lacking effective cytotoxic responses. Especially in Epstein-Barr virus (EBV)-negative cHL, the neoplastic Hodgkin-Reed-Sternberg (HRS) cells have lost protein expression of major histocompatibility complex (MHC) class I, enabling escape from cytotoxic T lymphocyte (CTL) responses. However, downregulation of...

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Identifiers

PMID: 18257895
DOI: 10.1111/j.1399-0039.2008.01005.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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