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Article

Classical Hodgkin lymphoma is associated with frequent gains of 17q

8 Aug 2003

Abstract excerpt

The etiology of Hodgkin lymphoma (HL) is poorly understood, and studies of the genetics of this disease have been hampered by the scarcity of the Hodgkin and Reed-Sternberg (HRS) cells within tumors. To determine whether recurrent genomic imbalances are a feature of HL, CD30-positive HRS cells were laser-microdissected from 20 classical Hodgkin lymphomas (cHLs) and four HL-derived cells lines and subjected to...

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PMID: 12939740
DOI: 10.1002/gcc.10266

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