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Article

Association of DDX58 177 C > T polymorphism with decreased risk of Epstein-Barr virus-related nodular sclerosis classical Hodgkin lymphoma.

Leukemia & lymphoma - 1 Feb 2017

Martin Paloma, Martínez-Velasquez Jimena, Coronado Maria Jose, Krsnik Isabel, Provencio Mariano, Navarro Belen, Moraru Manuela, Bellas Carmen, Vilches Carlos, Gomez-Lozano Natalia

Abstract excerpt

Classical Hodgkin lymphoma (cHL) is frequently related to Epstein-Barr virus (EBV) infection. Its malignant capacity is attributed to disruption of an EBV-host balance influenced by environmental and genetic drivers. EBV structures activate Type I interferon (IFN) pathway of the innate immunity, therefore, genetic polymorphisms could influence this response. We explored the impact of four single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27267403
DOI: 10.1080/10428194.2016.1190972

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