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Article

Presence of PDGFRA and DOG1 mutations in gastrointestinal stromal tumors among Chinese population.

International journal of clinical and experimental pathology - 1 Jan 2015

Li Jiehua, Zhang Haitian, Lu Yunfei, Chen Zhibai, Su Ka

Abstract excerpt

Approximately 15% of gastrointestinal stromal tumors (GIST) do not express KIT mutations and of these about 5 to 7% harbor mutations in PDGFRA. DOG1 was specifically expressed in GISTs. These cases require special attention for PDGFRA and DOG1 mutational status. Hundred cases of GIST were diagnosed between August 2007 and October 2012 at the First Affiliated Hospital of Guangxi Medical University. DNA from tumor...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26191287
PMCID: PMC4503158

Genes

PDGFRA
KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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