Article
Pathological characteristics of gastrointestinal stromal tumours with PDGFRA mutations.
Pathology - 1 Jan 2009
Kwon Ji Eun, Kang Hyun Ju, Kim Se Hoon, Lee Yong Chan, Hyung Woo Jin, Noh Sung Hoon, Kim Nam Kyu, Kim Hoguen
Abstract excerpt
AIMS: The aim of this study was to identify the characteristics of PDGFRA-mutated gastrointestinal stromal tumours (GISTs) in comparison with KIT-mutated GISTs. METHODS: A total of 151 GISTs were examined for KIT and PDGFRA mutations, and clinical and histopathological parameters were evaluated and analysed statistically according to mutation status. RESULTS: KIT and PDGFRA mutations were detected in 123 (81.5%)...
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