Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation assay of the novel gene DOG1 in gastrointestinal stromal tumors (GISTs).

Journal of gastroenterology - 1 Jan 2008

Miwa Shigeharu, Nakajima Takahiko, Murai Yoshihiro, Takano Yasuo, Sugiyama Toshiro

Abstract excerpt

BACKGROUND: Recently, the novel gene DOG1 has been found to be overexpressed in most gastrointestinal stromal tumors (GISTs) specifically within the field of soft tissue tumors. DOG1 might play a role in development of GISTs and have potential as a diagnostic marker and therapeutic target, but th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloride Channels
Share to Gastrointestinal Stromal Tumors
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Neoplasm Proteins

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 18648740
DOI: 10.1007/s00535-008-2195-4

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18648740-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation assay of the novel gene DOG1 in gastrointestinal stromal tumors (GISTs).PMID 18648740Read ↗

The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status.Semantic proximity Read ↗

A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.Semantic proximity Read ↗

Presence of PDGFRA and DOG1 mutations in gastrointestinal stromal tumors among Chinese population.Semantic proximity Read ↗

PDGFRA and KIT Mutation Status and Its Association With Clinicopathological Properties, Including DOG1.Semantic proximity Read ↗

Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or PDGFRA mutations.Semantic proximity Read ↗

DOG1 and PKC-θ are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors.Semantic proximity Read ↗

Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11.Semantic proximity Read ↗

DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors.Semantic proximity Read ↗

Diagnostic significance of DOG-1 and PKC-θ expression and c-Kit/PDGFRA mutations in gastrointestinal stromal tumoursSemantic proximity Read ↗

[Clinicopathologic features and immunophenotypes of CD117-negative gastrointestinal stromal tumor].Semantic proximity Read ↗

DOG1 overexpression is associated with mismatch repair deficiency and BRAF mutations but unrelated to cancer progression in colorectal cancer.Semantic proximity Read ↗

Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.