Article
Spectrum and prognostication of KIT and PDGFRA mutation in gastrointestinal stromal tumors.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 May 2008
Tzen C Y, Wang M N, Mau B L
Abstract excerpt
AIMS: Recent studies reported various mutation rates in gastrointestinal stromal tumors (GISTs) and inconsistent prognostic value of mutation in GIST patients. Our purpose was to analyze the frequency and spectrum of KIT and PDFGRA in a large series study and to determine if the presence of mutation and mutation type serve as prognostic factors in GIST patients. METHODS: A total of 134 GISTs were subjected to...
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