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Article

KIT and PDGFRA mutations and PDGFRA immunostaining in gastrointestinal stromal tumors.

Molecular medicine reports - 1 Jan 2000

Barreca Antonella, Fornari Alessandro, Bonello Lisa, Tondat Fabrizio, Chiusa Luigi, Lista Patrizia, Pich Achille

Abstract excerpt

In the present study, we investigated the association of PDGFRA and KIT mutations as well as PDGFRA immunohistochemical expression with clinicopathologic features and prognosis in a series of gastrointestinal stromal tumors (GISTs). Tumor DNA from 40 GISTs was sequenced for the presence of mutations in KIT exons 9, 11, 13 and 17, and in PDGFRA exons 12 and 18. Tissue sections were stained with polyclonal...

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Share to Gastrointestinal Stromal Tumors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21461555
DOI: 10.3892/mmr.2010.399

Genes

PDGFRA
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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