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Article

Supraphysiological hormonal status, anxiety disorders, and COMT Val/Val genotype are associated with reduced sensorimotor gating in women.

Psychoneuroendocrinology - 1 Oct 2015

Comasco Erika, Hellgren Charlotte, Olivier Jocelien, Skalkidou Alkistis, Sundström Poromaa Inger

Abstract excerpt

Pregnancy is a period characterized by a supraphysiological hormonal status, and greater anxiety proneness, which can lead to peripartum affective symptoms with dramatic consequences not only for the woman but also for the child. Clinical psychiatry is heavily hampered by the paucity of objective and biology-based intermediate phenotypes. Prepulse inhibition (PPI) of the startle response, a neurophysiological...

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Source

Identifiers

PMID: 26189199
DOI: 10.1016/j.psyneuen.2015.06.019

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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