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Article

Influence of catechol-O-methyltransferase Val158Met polymorphism on startle response in the presence of high estradiol levels.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jul 2013

Comasco Erika, Hellgren Charlotte, Sundström-Poromaa Inger

Abstract excerpt

INTRODUCTION: both human and animal studies have shown a somewhat complex COMT-by-sex interaction effect on brain function and dysfunction. A functional variation in the gene coding for the catechol-O-methyltransferase (COMT) enzyme, which metabolizes dopamine and noradrenaline, has been related to executive and emotional functions, and to sex dimorphism. AIM: to investigate if COMT Val158Met genotype influences...

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Source

Identifiers

PMID: 22831878
DOI: 10.1016/j.euroneuro.2012.06.015

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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