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Article

From genes to psychoses and back: the role of the 5HT2alpha-receptor and prepulse inhibition in schizophrenia.

European archives of psychiatry and clinical neuroscience - 1 Nov 2008

Maier Wolfgang, Mössner Rainald, Quednow Boris B, Wagner Michael, Hurlemann René

Abstract excerpt

Decomposition of schizophrenia into neurobiological vulnerability traits is necessary to understand the complex genetic underpinnings of this phenomenologically defined disorder. This issue is discussed with a focus on prepulse inhibition (PPI) as a neurobiological phenotype and the 5HT2a-recepto...

Read the complete abstract on PubMed

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Share to Acoustic Stimulation
Share to Genetic Predisposition to Disease
Share to Inhibition, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptor, Serotonin, 5-HT2A

Share to Reflex, Startle

Share to Schizophrenia

Share to Serotonin Receptor Agonists

Source

Identifiers

PMID: 18985293
DOI: 10.1007/s00406-008-5011-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18985293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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