Article

Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium

2025-03-02

Abstract excerpt

Acute Lung Injury (ALI) causes the highly lethal Acute Respiratory Distress Syndrome (ARDS) in children and adults, for which therapy is lacking. Children with Pediatric ARDS (PARDS) have a mortality rate that is about half of adults with ARDS. Improved ALI measures can be reproduced in rodent models with juvenile animals, suggesting that physiologic differences may underlie these outcomes. Here, we show that pneu...

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Literature Corpus work: 62ddfef8-fe1e-5457-9cd1-16ba15b3ab8f
DOI: 10.1101/2025.02.26.640349

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