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Article

WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury.

American journal of respiratory cell and molecular biology - 1 Oct 2012

Li Hui-Hua, Li Quan, Liu Pengyuan, Liu Yulin, Li Jin, Wasserloos Karla, Chao Wei, You Ming, Oury Tim D, Chhinder Sodhi, Hackam David J, Billiar Timothy R, Leikauf George D, Pitt Bruce R, Zhang Li-Ming

Abstract excerpt

Although strides have been made to reduce ventilator-induced lung injury (VILI), critically ill patients can vary in sensitivity to VILI, suggesting gene-environment interactions could contribute to individual susceptibility. This study sought to uncover candidate genes associated with VILI using a genome-wide approach followed by functional analysis of the leading candidate in mice. Alveolar-capillary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22700866
DOI: 10.1165/rcmb.2012-0127OC
PMCID: PMC3488625

Genes

TLR4
WNT1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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