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Article

The Formin DAAM Functions as Molecular Effector of the Planar Cell Polarity Pathway during Axonal Development in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jul 2015

Gombos Rita, Migh Ede, Antal Otilia, Mukherjee Anindita, Jenny Andreas, Mihály József

Abstract excerpt

Recent studies established that the planar cell polarity (PCP) pathway is critical for various aspects of nervous system development and function, including axonal guidance. Although it seems clear that PCP signaling regulates actin dynamics, the mechanisms through which this occurs remain elusive. Here, we establish a functional link between the PCP system and one specific actin regulator, the formin DAAM, which...

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Identifiers

PMID: 26180192
DOI: 10.1523/JNEUROSCI.3708-14.2015
PMCID: PMC4502256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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