Article
A signaling network for patterning of neuronal connectivity in the Drosophila brain.
PLoS biology - 1 Oct 2006
Srahna Mohammed, Leyssen Maarten, Choi Ching Man, Fradkin Lee G, Noordermeer Jasprina N, Hassan Bassem A
Abstract excerpt
The precise number and pattern of axonal connections generated during brain development regulates animal behavior. Therefore, understanding how developmental signals interact to regulate axonal extension and retraction to achieve precise neuronal connectivity is a fundamental goal of neurobiology. We investigated this question in the developing adult brain of Drosophila and find that it is regulated by crosstalk...
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