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Article

Drosophila Rac1 controls motor axon guidance.

Development (Cambridge, England) - 1 Feb 1998

Kaufmann N, Wills Z P, Van Vactor D

Abstract excerpt

Previous genetic studies of intersegmental nerve b development have identified several cell-surface proteins required for correct axon guidance to appropriate target muscles. Here we provide evidence that the small GTPase Drac1 also plays a key role in this guidance process. Neuronal expression of the dominant negative mutation Drac1(N17) causes axons to bypass and extend beyond normal synaptic partners. This...

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Identifiers

PMID: 9425140
DOI: 10.1242/dev.125.3.453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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