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Article

Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study.

AJNR. American journal of neuroradiology - 1 Oct 2010

Della Nave R, Ginestroni A, Tessa C, Giannelli M, Piacentini S, Filippi M, Mascalchi M

Abstract excerpt

BACKGROUND AND PURPOSE: HD entails damage of the WM. Our aim was to explore in vivo the regional volume and microstructure of the brain WM in HD and to correlate such findings with clinical status of the patients. MATERIALS AND METHODS: Fifteen HD gene carriers in different clinical stages of the disease and 15 healthy controls were studied with T1-weighted images for VBM and DTI for TBSS. Maps of FA, MD, and λ∥...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nerve Fibers, Myelinated

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Identifiers

PMID: 20488902
DOI: 10.3174/ajnr.A2128
PMCID: PMC7964981

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