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Article

Phenotype, Genotype, and Drug Resistance in Subtype C HIV-1 Infection.

The Journal of infectious diseases - 15 Jan 2016

Derache Anne, Wallis Carole L, Vardhanabhuti Saran, Bartlett John, Kumarasamy Nagalingeswaran, Katzenstein David

Abstract excerpt

BACKGROUND: Virologic failure in subtype C is characterized by high resistance to first-line antiretroviral (ARV) drugs, including efavirenz, nevirapine, and lamivudine, with nucleoside resistance including type 2 thymidine analog mutations, K65R, a T69del, and M184V. However, genotypic algorithms predicting resistance are mainly based on subtype B viruses and may under- or overestimate drug resistance in non-B...

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Source

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Identifiers

PMID: 26175454
DOI: 10.1093/infdis/jiv383
PMCID: PMC4690149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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