Article
Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study.
AIDS research and human retroviruses - 1 Sept 2016
Lam Edward P, Moore Cecilia L, Gotuzzo Eduardo, Nwizu Chidi, Kamarulzaman Adeeba, Chetchotisakd Ploenchan, van Wyk Jean, Teppler Hedy, Kumarasamy Nagalingeswaran, Molina Jean-Michel, Emery Sean, Cooper David A, Boyd Mark A
Abstract excerpt
We investigate mutations and correlates according to HIV-1 subtype after virological failure (VF) of standard first-line antiretroviral therapy (ART) (non-nucleoside/nucleotide reverse transcriptase inhibitor [NNRTI] +2 nucleoside/nucleotide reverse transcriptase inhibitor [N(t)RTI]). SECOND-LINE study participants were assessed at baseline for HIV-1 subtype, demographics, HIV-1 history, ART exposure, viral load...
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