Combining dependent F-tests for robust association of quantitative traits under genetic model uncertainty.

doi:10.1515/sagmb-2013-0001

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Article

Combining dependent F-tests for robust association of quantitative traits under genetic model uncertainty.

Statistical applications in genetics and molecular biology - 1 Apr 2014

Qu Long

Abstract excerpt

In association mapping of quantitative traits, the F-test based on an assumed genetic model is a basic statistical tool for testing association of each candidate locus with the trait of interest. However, the true underlying genetic model is often unknown, and using an incorrect model may cause serious loss of power. For case-control studies, it is known that the combination of several tests that are optimal for...

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Share to Case-Control Studies
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Share to Polymorphism, Single Nucleotide
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PMID: 24603842
DOI: 10.1515/sagmb-2013-0001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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