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Article

Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV

1 Jan 2020

Abstract excerpt

Chronic HIV-infected children suffer from premature aging and aging-related diseases. Viral replication induces an ongoing inflammation process, with the release of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), the activation of the immune system, and the production of proinflammatory cytokines. Although combined highly active antiretroviral therapy (ART) has...

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PMID: 32509884
DOI: 10.1155/2020/8041616

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