Article
Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cells.
Molecular medicine reports - 1 Oct 2015
Tian Lei, Chen Kan, Cao Jiatian, Han Zhihua, Gao Lin, Wang Yue, Fan Yuqi, Wang Changqian
Abstract excerpt
Oxidized low-density lipoprotein (oxLDL) is involved in the pathological phenotypic transformation of vascular smooth muscle cells in atherosclerosis. Galectin‑3 also has an important role in atherosclerosis. However, little is currently known regarding the effects of galectin‑3 on the oxLDL‑induced phenotypic transformation of vascular smooth muscle cells. In the present study, primary culture human umbilical...
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