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Article

Exosomal LINC01005 derived from oxidized low-density lipoprotein-treated endothelial cells regulates vascular smooth muscle cell phenotypic switch.

BioFactors (Oxford, England) - 1 Sept 2020

Zhang Zhiliang, Yi Dasong, Zhou Jiamin, Zheng Yaofu, Gao Zhiming, Hu Xiaoliang, Ying Guoqiu, Peng Xiaoping, Wen Tong

Abstract excerpt

Phenotype switch of vascular smooth muscle cells (VSMCs) plays an important role in the development of atherosclerosis (AS). Endothelial cells can regulate VSMC phenotypic switch by secreting exosomes, crucial mediators of intracellular communication. This study aimed to determine whether exosomal LINC01005 from oxidized low-density lipoprotein (ox-LDL)-treated human umbilical vein endothelial cells (HUVECs)...

Read the complete abstract on PubMed

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Share to Exosomes
Share to Human Umbilical Vein Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kruppel-Like Factor 4

Share to Kruppel-Like Transcription Factors

Share to Lipoproteins, LDL

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to RNA, Long Noncoding

Source

Identifiers

PMID: 32663367
DOI: 10.1002/biof.1665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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