Article
[eIF3a gene polymorphism and chemo-sensitivity to platinum-based drugs in ovarian cancer].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Jun 2015
Zhang Caiyi, Zhang Shufen, Liu Yingzi, Tian Yan, Li Xinguo, Zhang Yu
Abstract excerpt
OBJECTIVE: To investigate the relationship between the eukaryotic initiation factor 3a (eIF3a)polymorphisms and chemo-sensitivity to platinum-based drug in ovarian cancer. METHODS: Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis was performed to detect 57 cases of eIF3a polymorphic genotypes (rs3824830, rs77382849, rs10787899 and rs3740556) after platinum-based...
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