Article
[Polymorphisms of ERCC1 gene and outcomes in epithelial ovarian cancer patients with platinum-based chemotherapy].
Zhonghua fu chan ke za zhi - 1 Nov 2013
Qi Bing-li, Li Yan, Wang Na, Zhou Rong-miao, Hu Pei, Kang Shan
Abstract excerpt
OBJECTIVE: To explore the relationship among single nucleotide polymorphism (SNP) of excision repair cross-complementing 1(ERCC1) gene, chemotherapy sensitivity and clinical outcomes of epithelial ovarian cancer (EOC) patients treated with platinum. METHODS: Six tag single nucleotide polymorphisms (tagSNP;rs11615, rs3212986, rs735482, rs3212955, rs12610134 and ) were chose from ERCC1 gene. The genotypes...
