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Article

INSR gene polymorphisms correlate with sensitivity to platinum-based chemotherapy and prognosis in patients with epithelial ovarian cancer.

Gene therapy - 1 Jul 2017

Hu J-L, Hu X-L, Han Q, Guo A-Y, Wang C-J, Wen Y-Y, Cang S-D

Abstract excerpt

This study aimed to investigate the correlation between INSR gene polymorphisms on platinum-based chemotherapy sensitivity and prognosis in epithelial ovarian cancer (EOC). A total of 339 EOC patients receiving postoperative chemotherapy were recruited for the study. Tag single-nucleotide polymorphism of INSR gene was screened from HapMap combined with available literature. Frequency distribution of genotypes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Ovarian Epithelial

Share to Neoplasms, Glandular and Epithelial

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 28436941
DOI: 10.1038/gt.2017.26

Genes

INSR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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