Article
The significance of c.690G>T polymorphism (rs34529039) and expression of the CEBPA gene in ovarian cancer outcome.
Oncotarget - 11 Oct 2016
Konopka Bozena, Szafron Lukasz Michal, Kwiatkowska Ewa, Podgorska Agnieszka, Zolocinska Aleksandra, Pienkowska-Grela Barbara, Dansonka-Mieszkowska Agnieszka, Balcerak Anna, Lukasik Martyna, Stachurska Anna, Timorek Agnieszka, Spiewankiewicz Beata, El-Bahrawy Mona, Kupryjanczyk Jolanta
Abstract excerpt
The CEBPA gene is known to be mutated or abnormally expressed in several cancers. This is the first study assessing the clinical impact of CEBPA gene status and expression on the ovarian cancer outcome. The CEBPA gene sequence was analyzed in 118 ovarian cancer patients (44 platinum/cyclophosphamide (PC)-treated and 74 taxane/platinum (TP)-treated), both in tumors and blood samples, and in blood from 236 healthy...
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