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Article

Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patients.

Acta pharmacologica Sinica - 1 Mar 2015

Yin Ji-ye, Meng Xiang-guang, Qian Chen-yue, Li Xiang-ping, Chen Juan, Zheng Yi, Liu Rong, Zhou Hong-hao, Liu Zhao-qian

Abstract excerpt

AIM: Eukaryotic translation initiation factor 3 subunit A (eIF3a) plays critical roles in regulating the initiation of protein translation, and eIF3a is highly expressed in lung cancer. In this study, we investigated the association of the positively selected SNPs of eIF3a with the response to and toxicity of platinum-based chemotherapy in Chinese patients with non-small cell lung cancer (NSCLC). METHODS: SNP...

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Identifiers

PMID: 25732572
DOI: 10.1038/aps.2014.160
PMCID: PMC4349930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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