Article
Rs3802278 in 3'-UTR of SULF1 associated with platinum resistance and survival in Chinese epithelial ovarian cancer patients.
Journal of chemotherapy (Florence, Italy) - 1 Dec 2021
Zeng Feiyue, Liu Yujie, Ouyang Qianying, Sun Zeen, Zhang Keqiang, Li Xi, Liu Yingzi
Abstract excerpt
Ovarian cancer is the leading cause of death from gynecologic cancers, but platinum resistance remains a major obstacle in the chemotherapy of ovarian cancer. This study aims to examine the role of polymorphisms in sulfatase 1 (SULF1) in platinum resistance and survival in advanced epithelial ovarian cancer (EOC) patients. We genotyped 12 SNPs of SULF1 in 195 EOC patients treated with platinum using MassARRAY...
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