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Article

Effects of an opioid (proenkephalin) polymorphism on neural response to errors in health and cocaine use disorder.

Behavioural brain research - 15 Oct 2015

Moeller Scott J, Beebe-Wang Nicasia, Schneider Kristin E, Konova Anna B, Parvaz Muhammad A, Alia-Klein Nelly, Hurd Yasmin L, Goldstein Rita Z

Abstract excerpt

Chronic exposure to drugs of abuse perturbs the endogenous opioid system, which plays a critical role in the development and maintenance of addictive disorders. Opioid genetics may therefore play an important modulatory role in the expression of substance use disorders, but these genes have not been extensively characterized, especially in humans. In the current imaging genetics study, we investigated a single...

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Identifiers

PMID: 26164485
DOI: 10.1016/j.bbr.2015.07.004
PMCID: PMC4567394

Genes

PENK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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