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Article

Initial evidence that OPRM1 genotype moderates ventral and dorsal striatum functional connectivity during alcohol cues.

Alcoholism, clinical and experimental research - 1 Jan 2014

Ray Lara A, Courtney Kelly E, Hutchison Kent E, Mackillop James, Galvan Adriana, Ghahremani Dara G

Abstract excerpt

BACKGROUND: Endogenous opioids and striatal dopamine have been implicated in cue-induced alcohol craving and have been hypothesized to play a role in goal-directed, as opposed to habitual, alcohol use. This initial study examines dorsal and ventral striatal functional connectivity during alcohol-cue processing as a function of the A118G single-nucleotide polymorphism of the mu-opioid receptor (OPRM1) gene....

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Source

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Identifiers

PMID: 23876228
DOI: 10.1111/acer.12136
PMCID: PMC3808494

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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