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Article

Gene x disease interaction on orbitofrontal gray matter in cocaine addiction.

Archives of general psychiatry - 1 Mar 2011

Alia-Klein Nelly, Parvaz Muhammad A, Woicik Patricia A, Konova Anna B, Maloney Thomas, Shumay Elena, Wang Ruiliang, Telang Frank, Biegon Anat, Wang Gene-Jack, Fowler Joanna S, Tomasi Dardo, Volkow Nora D, Goldstein Rita Z

Abstract excerpt

CONTEXT: Long-term cocaine use has been associated with structural deficits in brain regions having dopamine-receptive neurons. However, the concomitant use of other drugs and common genetic variability in monoamine regulation present additional structural variability. OBJECTIVE: To examine variations in gray matter volume (GMV) as a function of lifetime drug use and the genotype of the monoamine oxidase A gene,...

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Source

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Identifiers

PMID: 21383264
DOI: 10.1001/archgenpsychiatry.2011.10
PMCID: PMC3127452

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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